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Moreover, NRF2 facilitates tumor growth by boosting anti-apoptotic and pro-survival mechanisms, exemplified in prostate cancer, where the interaction between estrogen receptor alpha (ERα) and NRF2 increases the expression of resistance-related genes, aiding in castration-resistant prostate cancer (CRPC) progression [38]
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Identification of an E-box motif as a transcriptional repressor element in the proximal promoter region of the GCLC gene in rat lung epithelial L2 cells
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