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A physician may consider reviewing: Weight history and body-composition goals A1C, fasting glucose, and fasting insulin when appropriate Cholesterol, triglycerides, and cardiovascular-risk markers Thyroid function Hormone status based on age, symptoms, and medical history Liver and kidney markers Inflammatory markers when clinically indicated CBC, iron, ferritin, vitamin B12, and vitamin D when appropriate Sleep quality and possible sleep apnea Exercise tolerance and recovery patterns Current medications and supplements Nutrition quality, protein intake, hydration, and alcohol use This evaluation helps determine whether MOTS-c belongs in the discussion or whether another health issue should be addressed first
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