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Full length FIP200 single particles showed an extended density with a C-shaped density at one end, corresponding to the dimeric FIP200NTD previously resolved (Shi et al., 2020)
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High cell density, on the other hand, inhibits mTORC1 and encourages SLC7A11 lysosomal degradation while improving SLC7A11 protein stability by lowering lysosomal degradation (46)
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