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Vitamin B-12 Cyanocobalamin 1000mcg/mL Injection - 30mL/Vial - Modern Medical Products
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RSV Shot
Choose Your Bundle::8oz | 5 Pack
Renal clearance: clearance of unchanged drug and metabolites Kidneys: most important organs for unchanged drug/drug metabolites elimination Water-soluble compounds exhibit more efficient renal excretion compared to lipid soluble compounds (emphasizing the importance of metabolic conversion of lipid-soluble drugs to water-soluble metabolites) Renal drug clearance is correlated with exogenous creatinine clearance or serum creatinine concentration Factors in renal excretion: Glomerular filtration important considerations: Fraction of free drug (compared to protein-bound drug)--when a drug is bound to protein it is not filtered Glomerular filtration rate Tubular secretion (active process) Drug/metabolite selectivity is important
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