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Pathogenic variants have been reported in the genes of dystrophin ( DMD ), sarcoglycans alpha, gamma, and delta ( SGCB , SGCG , and SGCD ), and genes of proteins that glycosylate the dystroglycans, such as Protein O-mannosyl transferase 1 and 2 ( POMT1 and POMT2 ), Protein O-mannose beta-1, 2-N-acetylglucosaminyltransferase ( POMGNT1 ), Fukutin ( FKTN ), Fukutin-related protein ( FKRP ), and Dystroglycan 1 ( DAG1 )
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