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DtxR DtxR (Diphtheria toxin repressor) family proteins form a phylogenetically conserved group of Fe II -and Mn II -regulated repressors prevalent largely in GC-rich Gram-positive bacteria and archaea, evolutionarily distinct from, but functionally analogous to, Fur family proteins (Figure 15A)

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In a presentation (PDF) to investors, Zealand notes that nearly 70% of clinical trial participants on the highest dose reported no gastrointestinal adverse events at any time